The Absolutely True Diary of a Part-Time Indian by Sherman Alexie
First line: I was born with water on the brain.
Summary: Junior is a budding cartoonist growing up on the Spokane Indian reservation. Born with a variety of medical problems, he is picked on by everyone but his best friend. Determined to receive a good education, Junior leaves the rez to attend an all-white school in the neighboring farm town where the only other Indian is the school mascot. Despite being condemned as a traitor to his people and enduring great tragedies, Junior attacks life with wit and humor and discovers a strength inside of himself that he never knew existed. Inspired by his own experiences growing up, award-winning author Sherman Alexie chronicles the contemporary adolescence of one unlucky boy trying to rise above the life everyone expects him to live. (summary is from the back of the book)
Thoughts: If you are a young adolescent, and are feeling sad, I highly recommend this book. I highly recommend anything that has unfiltered humor in it. It may be offensive, but offensive things are truly hilarious if you think from an objective point of mind. I found this book to be incredibly hilarious.
Warning: there is a lot of mild sexual humor in this, but it is incredibly hilarious.